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Response to Induction Therapy According to Genotype
| g/g | t/g | t/t | g/g vs t/g vs t/t | ||||
|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | p-value | |
| Phase 1 (course 1) response | |||||||
| CR | 72 | 82% | 150 | 85% | 135 | 75% | 0.062 |
| PR | 6 | 7% | 6 | 3% | 18 | 10% | 0.045 |
| Fail | 6 | 7% | 12 | 7% | 13 | 7% | 0.984 |
| Death | 4 | 5% | 8 | 5% | 13 | 7% | 0.477 |
| Unevaluable | 3 | 7 | 5 | ||||
| Phase 2 (course 2) cumulative response | |||||||
| CR | 58 | 73% | 130 | 78% | 122 | 70% | 0.261 |
| PR(M1) | 4 | 5% | 3 | 2% | 5 | 3% | 0.367 |
| Fail | 8 | 10% | 14 | 8% | 26 | 15% | 0.148 |
| Death | 10 | 13% | 20 | 12% | 21 | 12% | 0.993 |
| Unevaluable | 11 | 16 | 10 | ||||
