Table 1.
Validation of the recomLine VZV with clinically defined sera
| Assay | Result | Clinically defined sera | Serologically defined VZV-IgG/IgM Neg serad | ||||
|---|---|---|---|---|---|---|---|
| Chickenpox | Zoster | ||||||
| IgG | IgM | IgG | IgM | IgG | IgM | ||
| ELISA | Pos a | 5 | 5 | 18 | 9 | 0 | 0 |
| Inc b | 0 | 0 | 0 | 0 | 0 | 0 | |
| Neg c | 0 | 0 | 0 | 9 | 24 | 24 | |
| RecomLine VZV | Pos | 5 | 5 | 17 | 11 | 0 | 0 |
| Inc | 0 | 0 | 1 | 0 | 0 | 0 | |
| Neg | 0 | 0 | 0 | 7 | 24 | 24 | |
NOTE. Data are no. of serum samples.
a Pos: positive; bInc: inconclusive; cNeg: negative, d: as assayed by Siemens Enzygnost VZV IgG/IgM wcELISA.
RecomLine VZV strips were considered as positive when the intensity of the ORF68 band was higher than the cut-off band control.