Table 2.
hnRNP A2/B1 subcellular localization in HCC tissues with different histopathological grades by immunohistochemistry
| hnRNP A2/B1 distribution | Hepatitis | HCC | ||
|---|---|---|---|---|
| Well | Moderately | Poorly | ||
| N | 10 (100%) | 5 (42%) | 5 (22%) | 2 (14%) |
| N + C | 0 | 6 (50%) | 9 (39%) | 2 (14%) |
| C | 0 | 1 (8%) | 9 (39%) | 10 (72%) |
| Total | 10 | 12 | 23 | 14 |
1: Subcellular localization is described as N, nuclear localization; N+C, both nuclear localization and cytoplasmic localization observed in the same sample; C, cytoplasmic localization;
2: Three groups of HCC tissues were defined as Well-differentiation, Moderately-differentiation, Poorly-differentiation according to the degree of tumor differentiation;
3: P value of the correlation between hnRNP A2/B1 subcellular localization and the degree of HCC tumor differentiation, P = 0.0001, P < 0.05 (Wilcoxon rank sum test, statistical analysis see additional file 6).