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. 2010 Jul 9;10:64. doi: 10.1186/1471-2288-10-64

Table 2.

Adjustment for Differences in Patient Characteristics between Study Arms: Sensitivity to Prior Distributions

Type of Prior
Dataset Posterior Estimate
Median OR (95% credible interval)
Base Case Analysis:
" Reasonably Vague" (Grines)
Sensitivity Analysis:
"Fairly Unrestrictive" (Prevost)
Sensitivity Analysis:
" Vaguest"
Overall (μ) 0.37 (0.17,0.77) 0.37 (0.23,0.60) 0.37 (0.18,1.25)
Base Case
3 Covariatesa
(k = 44)
Randomised (θ1) 0.35 (0.17,0.63) 0.36 (0.21,0.59) 0.34 (0.13,0.74)
Non-Randomised (θ2) 0.39 (0.25,0.61) 0.38 (0.25,0.57) 0.40 (0.23,0.68)
Overall (μ) 0.45 (0.20,0.95) 0.47 (0.28,0.74) 0.44 (0.13,1.31)
Imputed
5 Covariatesb
(k = 79)
Randomised (θ1) 0.42 (0.18,0.78) 0.46 (0.25,0.73) 0.39 (0.14,0.87)
Non-Randomised (θ2) 0.49 (0.33,0.72) 0.49 (0.33,0.71) 0.49 (0.32,0.74)

a.male, age, cardiac disease, b.male, age, cardiac disease, pulmonary disease, renal disease

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