Table 1.
Organ | 11C-MePPEPa | 18F-FMPEP-d2 |
---|---|---|
Residence time (h) | Residence time (h) | |
Mean ± SD | Mean ± SD | |
Brain | 0.034±0.006 | 0.145±0.033 |
Cortical bone | 0.011±0.004 | 0.082±0.025 |
Gallbladder | 0.002±0.001 | 0.029±0.019 |
Heart wall | 0.007±0.002 | 0.017±0.003 |
Kidney | 0.009±0.003 | 0.034±0.007 |
Liver | 0.091±0.025 | 0.161±0.043 |
Lower large intestine | 0.000±0.000 | 0.012±0.003 |
Lung | 0.039±0.007 | 0.095±0.051 |
Red marrow | 0.019±0.002 | 0.198±0.075 |
Small intestine | 0.032±0.013 | 0.123±0.027 |
Spleen | 0.004±0.001 | 0.011±0.005 |
Trabecular bone | 0.003±0.001 | 0.020±0.006 |
Upper large intestine | 0.004±0.002 | 0.068±0.015 |
Urinary bladderb | - | 0.119±0.026 |
Remainder of body | 0.236±0.033 | 1.524±0.204 |
The residence time of 11 C-MePPEP in thyroid and lower large intestine is <0.001 h
Some organs could not be identified as source organs for both radioligands