Table 2.

Radiation dosimetry estimates for ¹¹C-MePPEP and ¹⁸F-FMPEP-d₂ each from seven healthy subjects

Organ	11C-MePPEP	18F-FMPEP-d2
	μGy/MBq	μGy/MBq
	Mean ± SD	Mean ± SD
Adrenals	3.3±0.1	13.3±0.4
Brain	8.0±1.5	26.3±5.4
Breasts	1.8±0.1	7.8±0.4
Gallbladder wall	8.7±3.1	60.7±29.2
LLI wall	2.5±0.1	21.1±1.9
Small intestine	11.6±3.8	38.0±5.5
Stomach	2.5±0.1	11.9±0.5
ULI wall	5.4±1.2	41.4±6.2
Heart wall	7.5±1.2	17.0±1.8
Kidneys	9.9±2.3	28.7±3.8
Liver	16.2±4.2	25.5±5.5
Lungs	11.0±1.7	21.9±8.6
Muscle	2.0±0.1	9.9±0.4
Ovaries	2.8±0.2	16.4±0.9
Pancreas	3.2±0.0	13.6±0.4
Red marrow	4.1±0.2	24.5±5.2
Bone surfaces	4.7±0.4	26.7±3.0
Skin	1.5±0.1	7.2±0.5
Spleen	7.9±2.2	18.3±4.8
Testes	1.6±0.2	9.3±0.7
Thymus	2.1±0.2	9.7±0.5
Thyroid	4.5±1.7	9.3±0.7
Urinary bladder walla	2.0±0.2	66.2±11.4
Uterus	2.6±0.1	17.1±0.7
Effective dose (μSv/MBq)	4.6±0.3	19.7±2.1

LLI lower large intestine, ULI upper large intestine

^aDetermined from the dynamic urinary bladder model with a voiding interval of 2.4 h