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Effect of IL-4 on MCP-1 expression in wild-type and NADPH oxidase knockout (NOX KO) mice. Mice were administered a single intraperitoneal injection of either PBS or 100 µg/kg of IL-4, and exposed for 4 h. The mRNA expression levels of MCP-1 in mouse aortas were determined by real-time RT-PCR. Values represent mean ± SEM (n = 5). *Statistically significant compared with the wild-type control (p < 0.05). #Statistically significant compared with NOX KO control (p < 0.05)
