Table I.
Polymer | Feed ratio M/D,Lb | Copolymer Composition (NMR) | Mn (kg/mol) | Mw (kg/mol) | |
---|---|---|---|---|---|
PLBMGA | P1 | 25/75 | 21/79 | 14 | 22 |
P2* | 25/75 | 22/78 | 16 | 35 | |
P3 | 35/65 | 30/70 | 11 | 16 | |
P4* | 35/65 | 35/65 | 21 | 41 | |
35/65 | 32/68 | 10 | 16 | ||
35/65 | 31/69 | 18 | 42 | ||
P7 | 50/50 | 44/56 | 10 | 15 | |
P8* | 50/50 | 46/54 | 20 | 51 | |
PLHMGA | P9 | 25/75 | 20/80 | 11 | 19 |
P10* | 25/75 | 20/80 | 13 | 30 | |
P11 | 35/65 | 31/69 | 8 | 13 | |
P12* | 35/65 | 33/67 | 20 | 37 | |
35/65 | 33/67 | 10 | 15 | ||
35/65 | 30/70 | 19 | 40 | ||
P15 | 50/50 | 47/53 | 4 | 7 | |
P16* | 50/50 | 46/54 | 19 | 45 |
aCopolymers used to study the effect of Mn on BSA release
b M monomer BMMG, D, L = D,L-lactide
cM/I = 10
*synthesized by using recrystallized monomer