Figure 2. Pressure-clamping modes and the pressure-volume curves of the balloon inside and outside the LV.
The LVP could be clamped at 0 mmHg continuously (not shown) and there were three other modes. Fig. Aa: clamping with a short pressure pulse from a background pressure of 0 mmHg. Fig. Ab: clamping with an isovolumic pressure profile (IPP). Fig. Ac: clamping with a short pressure pulse superimposed on an IPP. Panel B shows an example of the timing of LVP clamping relative to LVMAP. T is the coupling time defined as the time from the beginning of a pacing signal (te) to pressure pulse (tm). Panel C shows pressure-volume relations when the LV balloon was outside (▲) and inside (■) the LV. See text for more detail.