TABLE 1.
Results of complement factor B RI calculation by different methods
| Test | RI in μg/ml (90% CL) |
|
|---|---|---|
| Lower limit | Upper limit | |
| The Binding Sitea | 205 | 400 |
| Current ARUPb | 200 | 510 |
| Transformed parametric | 196 (179-214) | 589 (539-643) |
| Parametricc | 151 (119-184) | 555 (523-588) |
| Quantiles (0.025, 0.975) | 213 | 622 |
| Simple bootstrap | 213 (180-230) | 622 (509-662) |
| BCa (bias corrected accelerated) bootstrap | 207 (180-230) | 597 (509-662) |
a
Data were obtained from 29 British blood donors; samples were provided by the manufacturer for guidance purposes only.
b
ARUP Laboratories RI for the Beckman Array instrument.
c
Data were not normally distributed; therefore, the method was rejected.