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Effect of pknB on the MICs of β-lactam antibiotics against COL
| Antibiotic | MIC (μg/ml) for COL |
|||
|---|---|---|---|---|
| Wild type | pknB | pknB/pEPSA5 | pknB/pknB+ | |
| Oxacillin | 256 | 64 | 64 | 256 |
| Cloxacillin | 512 | 2 | 2 | 512 |
| Carbenicillin | 128 | 32 | 32 | 128 |
| Nafcillin | 256 | 64 | 64 | 256 |
| Ceftriaxone | 1,024 | 512 | 512 | 1,024 |
| Cephalothin | 128 | 64 | 64 | 128 |
