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Production of IL-8 after stimulation of cells with ATP-γ-S (1, 10, and 100 μM) for 6 or 24 h in UROtsa (A) and A498 (B) cells. The amount of IL-8 produced by ATP-γ-S is expressed as picograms per milliliter, and data are presented as means plus SEMs (error bars) (n = 3 or 4). Values that are statistically significantly different from the values for nonstimulated (NS) cells are indicated by brackets and asterisks as follows: *, P < 0.05; **, P < 0.01; and ***, P < 0.001.
