TABLE 3.
Estimation of bactericidal activity by prolongation of TTP in liquid culture for days 0 to 14, 0 to 2, and 2 to 14a
| Dosagec | PA-824 group |
Standard treatment groupb |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 200 mg |
600 mg |
1,000 mg |
1,200 mg |
All groups |
||||||||
| Mean h/day (±SD) | n | Mean h/day (±SD) | n | Mean h/day (±SD) | n | Mean h/day (±SD) | n | Mean h/day (±SD) | n | Mean h/day (±SD) | n | |
| EBA(0-14) | 3.818 (2.327) | 12 | 4.776 (2.879) | 14 | 4.865 (3.461) | 13 | 4.440 (2.169) | 12 | 4.494 (2.724) | 51 | 9.741 (5.249) | 8 |
| EBA(0-2) | 1.115 (15.256) | 13 | 5.788 (12.173) | 13 | 2.795 (9.230) | 11 | 1.400 (7.659) | 15 | 2.721 (11.225) | 52 | 24.125 (12.794) | 8 |
| EBA(2-14) | 3.833 (2.954) | 11 | 5.09 (2.768) | 13 | 4.069 (1.916) | 12 | 4.868 (3.224) | 12 | 4.491 (2.718) | 48 | 7.344 (4.660) | 8 |
a
n, number of participants with results.
b
For a definition of standard treatment, see the text.
c
Note that EBA(0-14) can deviate from the arithmetic sum of EBA(0-2) and EBA(2-14) due to missing data points.