TABLE 4.

Selected genes from the microarray analysis of genes expressed differently in the presence of 4 μg/ml indolicidin in the parR mutant compared to the WT^a

GeneID	Gene name	Fold changeb	P value	Description
PA0282	cysT	−2.3	0.03	Sulfate transport protein CysT
PA0517	nirC	2.7	0.04	Probable c-type cytochrome precursor
PA0523	norC	6.0	0.01	Nitric oxide reductase subunit C
PA0524	norB	10.7	0.009	Nitric oxide reductase subunit B
PA1559		−4.2	<0.001	Hypothetical protein
PA1560		−2.9	<0.001	Hypothetical protein
PA1797		−3.3	<0.001	Hypothetical protein
PA3392	nosZ	2.1	0.04	Nitrous oxide reductase precurser
PA3396	nosL	2.0	0.04	NosL protein
PA3446		−5.8	0.0007	Hypothetical protein
PA3552	arnB	−1.6	0.0009	Hypothetical protein
PA3553	arnC	−2.0	<0.001	Probable glycosyltransferase
PA3554	arnA	−2.5	<0.001	Hypothetical protein
PA3555	arnD	−2.9	<0.001	Hypothetical protein
PA3556	arnT	−2.1	0.003	Inner membrane l-Ara4N transferase ArnT
PA3559	pmrE	−3.3	<0.001	Probable nucleotide sugar dehydrogenase
PA3920		2.3	0.0059	Membrane proteins/transport of small molecules
PA4661	pagL	−2.5	<0.001	Lipid A 3-O-deacylase
PA4773		−5.1	<0.001	Hypothetical protein
PA4774		−7.4	<0.001	Hypothetical protein
PA4775		−3.3	<0.001	Hypothetical protein
PA4776	pmrA	−2.1	0.003	Two-component system response regulator
PA4777	pmrB	−1.7	0.002	Two-component system signal sensor kinase
PA4782		−6.7	<0.001	Hypothetical protein

^aThe full list of dysregulated genes is given in Table S1 in the supplemental material.

^bFold change in gene expression in the presence of 4 μg/ml indolicidin in the parR mutant compared to gene expression in the presence of 4 μg/ml indolicidin in the WT.