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. 2010 May 24;54(8):3493–3497. doi: 10.1128/AAC.00080-10

TABLE 2.

Epidemiological data and resistance phenotypes of all P. aeruginosa isolates with reduced susceptibility to imipenem and resistance to ceftazidime

Isolate Specimen Date of recovery Warda MBL enzymeb MIC (μg/ml)c
PIP TZP CAZ FEP ATM IMP MEM COL AMK GEN TOB CIP
MBL-producing isolates
    PA399 Urine November 2007 Urology VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 8 ≥16 ≥16 ≥4
    PA462 Ascitic fluid June 2008 General surgery VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 4 ≥16 ≥16 ≥4
    PA465 Drainage July 2008 General surgery VIM-2 ≥128 64 ≥64 ≥64 16 ≥16 ≥16 2 8 ≥16 ≤1 ≥4
    PA469 Wound August 2008 General surgery VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 8 ≥16 ≥16 ≥4
    PA475 Wound September 2008 General surgery VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 4 ≥16 ≥16 ≥4
    PA477 Drainage September 2008 General surgery VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 8 ≥16 ≥16 ≥4
    PA481 Urine October 2008 Urology VIM-2 ≥128 ≥128 ≥64 ≥64 16 ≥16 ≥16 1 8 ≥16 ≥16 ≥4
    PA500 Tracheal secretion February 2009 Surgical ICU VIM-1 ≥128 ≥128 ≥64 ≥64 4 ≥16 ≥16 1 ≤2 ≥16 8 ≥4
    PA510 Tracheal secretion May 2009 Medical ICU VIM-2 ≥128 ≥128 ≥64 ≥64 ≥64 ≥16 ≥16 1 4 ≥16 ≥16 ≥4
MBL-negative isolates
    PA459 Tracheal secretion June 2008 Surgical ICU − ≥128 ≥128 32 8 16 ≥16 8 1 2 1 1 0.25
    PA460 Wound June 2008 General surgery − ≥128 ≥128 32 16 16 ≥16 8 1 4 ≥16 ≥16 ≥4
    PA479 Urine October 2008 General surgery − ≥128 ≥128 ≥64 ≥64 32 8 ≥16 1 8 ≥16 ≥16 ≥4
    PA483 Wound October 2008 Surgical ICU − ≥128 ≥128 ≥64 32 64 ≥16 ≥16 1 2 1 1 0.25
    PA494 Urine December 2008 Neurosurgery − ≥128 ≥128 32 8 16 ≥16 8 1 8 8 1 ≥4
    PA507 Drainage April 2009 Surgical ICU − ≥128 ≥128 32 16 16 ≥16 4 1 16 ≥16 1 0.25
    PA509 Wound May 2009 Internal medicine − ≥128 ≥128 32 16 8 ≥16 ≥16 2 64 ≥16 ≥16 ≥4
a

ICU, intensive care unit.

b

The type of MBL enzyme is given for the isolates that produce MBL. Some isolates did not produce MBL (−).

c

Abbreviations for antimicrobial agents: PIP, piperacillin; TZP, piperacillin-tazobactam; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; IMP, imipenem; MEM, meropenem; COL, colistin; AMK, amikacin; GEN, gentamicin; TOB, tobramycin; CIP, ciprofloxacin.