FIG. 1.

Impact of FKS1 modulation on antifungal susceptibility in C. albicans biofilms. FKS1-modulated biofilms were grown in 96-well plates for 6 h and treated with serial dilutions of anidulafungin (A), flucytosine (B), or amphotericin B deoxycholate (C) for an additional 24 h. Endpoints were assessed using an XTT assay, and data are shown as percentages of biofilm growth relative to growth of untreated controls. Assays were performed in triplicate, and each error bar represents one standard error. Statistical significance was determined by analysis of variance with pairwise comparisons using the Holm-Sidak method. *, P < 0.05.