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. 2010 May 24;30(15):3758–3766. doi: 10.1128/MCB.00121-10

FIG. 7.

FIG. 7.

Redox modulators, pharmacological agents that restore the intracellular redox state of mutant cell lines to normal levels. (A) FRET imaging of CHO cells at 37°C treated with TSA (50 nM), VE (50 M), and 4PBA (5 mM). Bar, 10 μm. (B) The values represent the relative FRET values of Redoxfluor normalized to the value from nontreated CHO-K1 (wild type) set arbitrarily to 1.0. (C) The relative abundance of GST mRNA standardized against the levels for ACTB. (D) Intracellular GSH/GSSG ratio. In panels B and C, values represent the means ± standard deviations (n = 3).