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i.n. infection of BALB/c and CAST/EiJ mice with MPXV-Z79-CB2. Groups of five to ten 5- to 6-week-old female mice were infected i.n. with doses of MPXV-Z79-CB2 ranging from 102 to 106 PFU. Another group was mock infected. Animals were monitored daily for weight loss and death for 18 days. (A) Weight loss in BALB/c mice; (B) weight loss in CAST/EiJ mice; (C) survival of CAST/EiJ mice.
