TABLE 1.

Anthrax toxin neutralization titers^a

Priming virus (day 0)b	Titer (day 28)	Boosting virus (day 42)	Titer
			Day 56	Day 77
rab-RBD	<100	rab-RBD	<100	<100
		inf-RBD	<100	<100
		inf-LEF	<100	<100
		inf-MIX	<100	<100
inf-RBD	166	rab-RBD	1,038	7,039
		inf-RBD	163	<100
inf-LEF	<100	rab-RBD	<100	<100
		inf-LEF	<100	<100
		vv-LEF	<100	<100
inf-MIX	<100	rab-RBD	165	241
		inf-MIX	<100	<100
		vv-MIX	165	<100
Wild-type influenza virus	<100
Naive serum	<100

^aThe mice were primed with the indicated virus on day 0 and then boosted with the indicated virus on day 42. The anthrax toxin neutralization titers at days 28, 56, and 77 are shown. The titers are expressed as the reciprocal of the dilution that protected 50% of the cells in an MTT assay (see Materials and Methods). A neutralizing titer less than 100 is considered negative and is reported as <100.

^b“Day” refers to days after initial inoculation.