TABLE 3.
Distribution of moxifloxacin MICs determined by two phenotypic methodsa
| 7H10 MIC of moxifloxacin (μg/ml) | No. of isolates with indicated MGIT960 MIC (μg/ml) |
||||
|---|---|---|---|---|---|
| ≤0.125 | 0.25 | 0.5 | 1 | >1 | |
| ≤0.125 | 14 | 1 | 0 | 0 | 0 |
| 0.25 | 4 | 0 | 0 | 0 | 0 |
| 0.5 | 3 | 0 | 0 | 0 | 0 |
| 1 | 0 | 0 | 0 | 0 | 0 |
| 2 | 0 | 0 | 0 | 1 | 2 |
| >2 | 0 | 0 | 0 | 1 | 3 |
a
Twenty-nine isolates were tested. Italics indicate the previously published breakpoint concentration and cutoff for resistance. Boldface indicates the proposed breakpoint stemming from the current study, 0.5 μg/ml for moxifloxacin (MGIT960). 7H10, Middlebrook 7H10 agar dilution method; MGIT960, mycobacterium growth indicator tube.