TABLE 2.
Clinical diagnostic truth, based on the composite reference methods algorithm to determine the presence or absence of NoV in specimens collected between February and December 2008
| Reference methoda |
Clinical diagnostic truth | ||
|---|---|---|---|
| rRT-PCR | Conventional RT-PCR/sequence | EM | |
| +/− | + | + | + |
| +/− | +/− | + | + |
| +/− | + | −/NA | + |
| − | − | − | − |
| + | − | − | Indeterminateb |
a
+/−, positive or negative by the indicated methodology; NA, not available.
b
If the EM testing result was negative, then it was counted against IDEIA test performance in the positive and negative agreement calculation regardless of the IDEIA norovirus kit test result, unless there was other information (e.g., epidemiologic information) available to assist in establishing diagnostic truth.