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. 2010 Jun 23;48(8):2934–2939. doi: 10.1128/JCM.00201-10

FIG. 1.

FIG. 1.

Representative patterns obtained by the MTBDRsl assay. Lane 1, negative control; lanes 2 and 3, FQ-, EMB-, and KAN-susceptible strains; lanes 4, 5, 6, and 7, resistant strains (lane 4, resistant to FQ and EMB; lane 5, resistant to FQ, AMP/CMP, and EMB; lane 6, resistant to EMB; lane 7, resistant to FQ and EMB); lanes 8, 9, 10, and 11, strains containing wild-type and FQ-resistant populations. Specific probes are as follows: CC, conjugate control; AC, amplification control; TUB, Mycobacterium tuberculosis complex control; gyrA, gyrA gene amplification control; gyrA WT1 to WT3, gyrA wild-type probes; gyrA MUT1, gyrA MUT2, and gyrA MUT3A to MUT3D, gyrA mutant probes for A90V, S91P, D94A, D94N, D94Y-D94G, and D94H, respectively; rrs, rrs amplification control; rrs WT1 and WT2, rrs wild-type probes; rrs MUT1 and MUT2, rrs mutant probes for A1401G and G1484T, respectively; embB, embB amplification control; embB WT1, embB wild-type probe I codon 306; embB MUT1A and embB MUT1B, embB mutant probes for M306I and M306V, respectively.