TABLE 4.
MTBDRsl pattern of 53 phenotypically ethambutol-resistant and 5 phenotypically kanamycin-resistant isolates
| Drug (gene) and MTBDRsl hybridization patterna | Codon mutation | No. (%) of isolates with MTBDRsl hybridization pattern |
|---|---|---|
| Ethambutol (embB) | ||
| ΔWT | ATG306ATC/ATT | 5 (9.4) |
| ΔWT + MUT1A | M306I | 5 (9.4) |
| ΔWT + MUT1B | M306V | 21 (39.6) |
| WT + MUT1A | None (WT) + M306I | 1 (1.9) |
| WT + MUT1B | None (WT) + M306V | 2 (3.8) |
| WT + MUT1A + MUT1B | None (WT) + M306I + M306V | 1 (1.9) |
| WT | None (WT) | 18 (34.0) |
| Total | 53 (100) | |
| Kanamycin (rrs) | ||
| ΔWT1 + WT2 + MUT1 | A1401G | 4 (44.4) |
| WT1 + WT2 + MUT1 | None (WT) + G1484T | 1 (11.1) |
| Total | 5 (100) |