TABLE 2.
Ability of commercial systems to infer carbapenemase production in isolates of Enterobacteriaceae with defined carbapenem resistance mechanismsa
| Mechanism | No. of isolates |
|||||||
|---|---|---|---|---|---|---|---|---|
| Phoenix |
MicroScan NM36 |
MicroScan NBC39 |
Vitek 2 |
|||||
| Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | |
| KPC (n = 8) | 8 | 0 | 8 | 0 | 8 | 0 | 8 | 0 |
| MBL (IMP, VIM, or NDM; n = 20) | 20 | 0 | 19 | 1b | 20 | 0 | 16 | 4b |
| OXA-48 (n = 11) | 11 | 0 | 6 | 5 | 4 | 7 | 5 | 6 |
| E. coli/Klebsiella spp., ESBL, porin loss (n = 10) | 10 | 0 | 10 | 0 | 8 | 2 | 8 | 2 |
| Enterobacter spp., AmpC/ESBL, porin loss (n = 6) | 6 | 0 | 5 | 1 | 5 | 1 | 2 | 4 |
There were 55 test isolates. Phoenix flagged likely carbapenemase producers as potentially having an MBL, whereas the MicroScan flagged them as potentially having KPC enzymes. These inferences were taken to mean carbapenemase positive.
All IMP types.