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. 2010 Jun 9;48(8):2999–3002. doi: 10.1128/JCM.00341-10

TABLE 2.

Ability of commercial systems to infer carbapenemase production in isolates of Enterobacteriaceae with defined carbapenem resistance mechanismsa

Mechanism No. of isolates
Phoenix
MicroScan NM36
MicroScan NBC39
Vitek 2
Positive Negative Positive Negative Positive Negative Positive Negative
KPC (n = 8) 8 0 8 0 8 0 8 0
MBL (IMP, VIM, or NDM; n = 20) 20 0 19 1b 20 0 16 4b
OXA-48 (n = 11) 11 0 6 5 4 7 5 6
E. coli/Klebsiella spp., ESBL, porin loss (n = 10) 10 0 10 0 8 2 8 2
Enterobacter spp., AmpC/ESBL, porin loss (n = 6) 6 0 5 1 5 1 2 4
a

There were 55 test isolates. Phoenix flagged likely carbapenemase producers as potentially having an MBL, whereas the MicroScan flagged them as potentially having KPC enzymes. These inferences were taken to mean carbapenemase positive.

b

All IMP types.