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Cell type-specific iCre expression in embryos and newborn mice. Immunostaining was performed for iCre in cross-sections from the neck region of embryos at d 12.5 (A and B) and tibia (C and D) and liver (E and F) of newborn mice. Control (A, C, and E) and conditional mutant (B, D, and F) mice are shown. Arrows indicate iCre-specific immunostaining in bone-forming regions. iCre was not detectable in the livers of conditional mutants.
