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Dynamic histomorphometry demonstrates reduced bone formation and bone size in conditional mutant mice at 2 wk of age. BFR, Bone formation rate; BS, bone surface; MAR, mineral apposition rate. Controls, n = 6–8; conditional mutants, n = 8–12. *, P < 0.05 vs. control; #, P ≤ 0.07 vs. control. Data are expressed as a percent of controls and presented as mean ± sem.
