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. 2010 Jun 10;26(16):1965–1974. doi: 10.1093/bioinformatics/btq308

Fig. 9.

Fig. 9.

Comparison of prediction efficiency in NRPDB and E. coli genome. The NRPDB contained 48 true TMBBs and 14 190 non-TMBBs. The E.coli genome has 36 known confirmed TMBBs and 2385 non-TMBBs; the remaining 2718 are unknown (114 were eliminated for being either too short or too long). This analysis only compared the prediction efficiency results for those E.coli genes, which were readily classifiable to the results of the NRPDB analysis. The PPV and MCC show that the Freeman–Wimley algorithm is much more efficient at distinguishing TMBB sequences from non-TMBB sequences in a genomic database than in the NRPDB.