Table 2.

Change in Disease Activity Scores with Physician-rated and Parent-rated cSLE Course ^†

Change in Core Set Variables‡	(A) Worsening (n of episodes = 89)	(B) No Change (n of episodes = 348)	(C) Improvement (n of episodes = 89)	(A) vs. (B)¶	(A) vs. (C)¶	(B) vs. (C)¶
Physician-rated Change in cSLE Course
VASMD	1.23 ± 0.12	−0.18 ± 0.06	−1.01 ± 0.12	< 0.001	< 0.001	< 0.001
ECLAM	0.97 ± 0.16	0.02 ± 0.08	−1.12 ± 0.16	< 0.001	< 0.001	< 0.001
SLEDAI	1.56 ± 0.33	−0.09 ± 0.17	−2.27 ± 0.33	< 0.001	< 0.001	< 0.001
SLAM	1.78 ± 0.76	−0.01 ± 0.38	−1.78 ± 0.78	< 0.1	< 0.01	NS *
BILAGLiang	3.23 ± 0.70	−0.62 ± 0.35	−4.61 ± 0.70	< 0.001	< 0.001	< 0.001
BILAGGladman	1.18 ± 0.23	−0.08 ± 0.12	−1.22 ± 0.23	< 0.001	< 0.001	< 0.001
BILAGStoll	1.85 ± 0.39	−0.35 ± 0.20	−2.79 ± 0.39	< 0.001	< 0.001	< 0.001
Parent-rated Change in Patient Well-being
VASMD	0.42 ± 0.18	−0.03 ± 0.09	−0.24 ± 0.09	< 0.1	< 0.01	NS
ECLAM	0.65 ± 0.22	0.03 ± 0.10	−0.25 ± 0.11	< 0.05	< 0.001	NS
SLEDAI	1.04 ± 0.45	−0.03 ± 0.21	−0.66 ± 0.23	< 0.1	< 0.01	NS
SLAM	1.83 ± 0.98	−0.29 ± 0.46	−0.04 ± 0.50	NS	NS	NS
BILAGLiang	2.98 ± 0.93	−0.34 ± 0.44	−1.81 ± 0.47	< 0.01	< 0.001	< 0.1
BILAGGladman	1.22 ± 0.30	0.02 ± 0.14	−0.43 ± 0.15	< 0.01	< 0.001	< 0.1
BILAGStoll	1.53 ± 0.53	−0.29 ± 0.25	−0.97 ± 0.27	< 0.01	< 0.001	NS

^†For additional information please see footnotes of Table 1

^‡Values presented are means and standard errors (SE)

^*NS = Not significant.

^¶P-values are based on mixed models using the Tukey-procedure for post-hoc correction