Table 2. NPL and LOD scores for linkage analysis of 43 families with left ventricular outflow tract malformations.
| Marker | Physical position (bp) | Genetic position (cM) | LOD | alpha | HLOD | NPLS |
|---|---|---|---|---|---|---|
| D2S168 | 11 362 901 | 29.14 | −28.0859 | 0.203 | 0.3557 | 1.4770 |
| −3.5028 | 0.409 | 1.2637 | 1.3787 | |||
| D2S305 | 19 281 858 | 42.58 | −15.8609 | 0.309 | 1.4151 | 1.4137 |
| −2.7541 | 0.415 | 1.7789 | 1.5540 | |||
| D2S165 | 28 456 785 | 52.00 | −7.1025 | 0.492 | 2.2007 | 1.9339 |
| −3.3247 | 0.475 | 1.8423 | 1.9227 | |||
| D2S367 | 34 294 651 | 60.55 | −25.0467 | 0.328 | 1.1383 | 1.9927 |
| −8.9166 | 0.353 | 1.2083 | 2.0973 | |||
| D2S2259 | 42 850 050 | 70.36 | −19.2458 | 0.347 | 1.2153 | 2.2583 |
| −12.6881 | 0.342 | 1.1562 | 2.1626 | |||
| D2S391 | 46 264 871 | 75.93 | −20.5398 | 0.327 | 1.0792 | 2.0870 |
| −8.4940 | 0.302 | 0.7888 | 1.4996 | |||
| D10S208 | 31 720 082 | 59.63 | −13.6236 | 0.0990 | 0.0424 | 1.5883 |
| −6.0721 | 0.3330 | 0.4980 | 1.9308 | |||
| D10S196 | 51 812 273 | 69.37 | −17.3778 | 0.2400 | 0.2607 | 2.1327 |
| −4.7211 | 0.3900 | 0.7525 | 2.2819 | |||
| D10S1652 | 64 077 500 | 80.04 | −19.2786 | 0.3440 | 0.8879 | 2.5707 |
| −9.2428 | 0.2970 | 0.5244 | 2.1479 | |||
| D10S537 | 72 065 333 | 89.34 | −31.5072 | 0.1130 | 0.0730 | 1.7875 |
| −10.1712 | 0.1810 | 0.2735 | 1.0040 | |||
| D16S3075 | 12 116 698 | 29.42 | −30.7294 | 0.0670 | 0.0335 | 0.5389 |
| −9.1089 | 0.3680 | 0.9469 | 1.1543 | |||
| D16S3103 | 17 380 963 | 37.82 | −17.7972 | 0.4580 | 1.8967 | 1.8979 |
| −4.3886 | 0.5210 | 2.0960 | 1.9359 | |||
| D16S3046 | 20 793 898 | 43.87 | −14.0909 | 0.4770 | 1.7185 | 1.9631 |
| −2.5359 | 0.5600 | 2.2517 | 1.8773 | |||
| D16S3068 | 25 468 101 | 51.16 | −21.4954 | 0.2900 | 0.6198 | 1.5409 |
| −6.6037 | 0.4070 | 1.1164 | 1.6606 | |||
| D16S3136 | 49 263 733 | 62.37 | −11.2392 | 0.3820 | 1.2381 | 1.8806 |
| −8.8130 | 0.4070 | 1.4464 | 1.9403 | |||
| D16S415 | 52 228 161 | 67.57 | −17.8935 | 0.4010 | 1.4825 | 2.0329 |
| −7.6875 | 0.3270 | 0.6573 | 1.2151 |
Alpha, proportion of families contributing to linkage signal in HLOD score; bp, base pairs, based on NCBI reference genome sequence, build 36; cM, genetic recombination distance in centiMorgans; LOD, lod score assuming homogeneity (all families contributing to locus).