Figure 6. Two enzymes with similar substrate binding sites.
The figure depicts the active sites of the teichoic acid phosphorylcholine esterase Pce from Streptococcus pneumoniae (2bib, left) and a methionine aminopeptidase from Escherichia coli (2gg8, right). These unrelated enzymes use similar mechanisms and have analogous binding modes for the substrate (left) and an inhibitor (right).
