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. 2010 Aug 5;5(8):e11980. doi: 10.1371/journal.pone.0011980

Figure 7. OXTR deficiency does not alter the morphology of taste buds.

Figure 7

Vallate papillae were harvested from mice of the following genotypes: wildtype (Oxtr/Oxtr), heterozygous (Oxtr/Y), or homozygous for the OXTR-YFP knock-in allele (Y/Y). The Y/Y mice have no functional allele for OXTR, and are OXTR knockouts. We immunostained sections of vallate papillae for NTPDase2 (A), PLCβ2 (B), and aromatic amino acid decarboxylase (AADC) (C). NTPDase2 and PLCβ2 are markers for Glial-like and Receptor cells, respectively. AADC is a marker for Presynaptic cells [18], [29]. Sections from all three genotypes immunostained with anti-GFP (D) are shown for reference. We observed no difference in size, shape, or number of cells of each type across genotypes. Scale bars, 20 µm. Bar in C applies to A–C.