Table 1. Baseline characteristics of the CHARGE Consortium discovery cohorts.* .
ARIC (N = 8,122) | FHS (N = 2,866) | RS (N = 4,378) | AGES (N = 3,219) | CHS (N = 3,370) | |
N (%) | |||||
Men | 3,831 (47) | 1,372 (48) | 1,690 (39) | 1,352 (42) | 1,339 (40) |
Hypertension | 2,201 (27) | 575 (20) | 2,478 (57) | 1,127 (35) | 1,533 (45) |
Using hypertension medications | 2,076 (26) | 247 (9) | 1,447 (26) | 208 (6) | 1,201 (36) |
Hypomagnesemia (<0.7 mmol/L) | 638 (8) | 22 (1) | 411 (9) | NA | NA |
Mean±SD | |||||
Age (y) | 54±5.7 | 43±9.8 | 70±9.0 | 51±6.4† | 72±5.4 |
BMI (kg/m2) | 27±4.9 | 25±4.0 | 26±3.7 | 25±3.5 | 26±4.5 |
eGFR (ml/min/1.73 m2) | 90±17.9 | 103±36.1 | 71±17.2 | 72±20.0† | 80±22.6 |
SBP (mmHg) | 119±17.0 | 121±16.0 | 139±22.1 | 132±16.9 | 135±21.0 |
DBP (mmHg) | 72±10.0 | 78±9.6 | 74±11.7 | 83±9.6 | 70±11.4 |
Magnesium (mmol/L) | 0.83±0.07 | 0.94±0.08 | 0.81±0.09 | NA | NA |
AGES, Age, Gene/Environment Susceptibility—Reykjavik Study; ARIC, The Atherosclerosis Risk in Communities Study; BMI, body mass index; CHARGE, Cohorts for Heart and Aging Research in Genomic Epidemiology; CHS, The Cardiovascular Health Study; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FHS, The Framingham Heart Study; NA, not available; RS, The Rotterdam Study; SBP, systolic blood pressure; SD, standard deviation.
*Characteristics are reported for the population with magnesium concentrations for ARIC, FHS, and RS and for the population with information on blood pressure for CHS and AGES.
†: Age reported is at the time of blood pressure measurement. eGFR was measured at an average age of 75.