Table 6. Joint genotype table for locus 1 versus locus 3 in CPD cases (heavy smokers) and controls (light smokers).
| Locus 3: rs588765 or correlates | ||||||
| RR | RC | CC | ||||
| Locus 1: rs16969968 or correlates | N cases/N controls1 | Odds ratio (95% CI)2 | N cases/N controls1 | Odds ratio (95% CI)2 | N cases/N controls1 | Odds ratio (95% CI)2 |
| RR | 605/672 | 1.00 (ref) | 2317/2237 | 1.15 (1.02–1.30) | 2259/1783 | 1.41 (1.24–1.60) |
| RC | 2302/1757 | 1.46 (1.28–1.65) | 4295/2760 | 1.73 (1.53–1.95) | 37/34 | 1.21 (0.75–1.95) |
| CC | 2185/1073 | 2.26 (1.98–2.58) | 48/28 | 1.90 (1.18–3.07) | 2/1 | 2.22 (0.20–24.56) |
R = reference allele.
C = coded allele.
1
The number of CPD cases and CPD controls with the specified two-locus genotype combination.
2
The odds ratio and 95% CI when the reference joint genotype is RR at locus 1 and RR at locus 3.