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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Pacing Clin Electrophysiol. 2009 Dec 16;33(3):274–285. doi: 10.1111/j.1540-8159.2009.02642.x

Figure 6. Electrophysiological characteristics of CACNB2b-D601E cardiac calcium channel polymorphism.

Figure 6

A: Whole-cell patch-clamp current recorded from calcium WT (α1C/β2A/ α2δ) and D601E channels in response to the voltage clamp protocol depicted as inset. B: Current density-voltage relationship for WT (open circles, n = 8) and D601E (filled circles, n = 7) in TSA201 cell line. C: Vertical bar graph of current density in 3 different time points at the voltage of 0mV. There was no significantly difference of peak current density amplitude between WT and D601E (P>0.05), but distinct difference were observed in 50 ms and 300 ms (**P<0.01).