Table 1.
Maternal and Infant HFE and TF Genotype Frequencies
| Mother | Infant | ||||
|---|---|---|---|---|---|
| Genotype | Number | % | Genotype | Number | % |
| HFE (C282Y) | HFE (C282Y) | ||||
| C282 Wildtype (CC) | 523 | 98.1 | C282 Wildtype (CC) | 378 | 96.9 |
| C282Y Heterozygous (CY) | 10 | 1.9 | C282Y Heterozygous (CY) | 10 | 3.1 |
| C282Y Homozygous (YY) | 0 | 0 | C282Y Homozygous (YY) | 0 | 0 |
| Hardy-Weinberg equilibrium: χ2 = 0.05, p = 0.83 | Hardy-Weinberg equilibrium: χ2 = 0.10, p = 0.76 | ||||
| HFE (H63D) | HFE (H63D) | ||||
| H63 Wildtype (HH) | 452 | 85.0 | H63 Wildtype (HH) | 319 | 82.2 |
| H63 D Heterozygous (HD) | 77 | 14.5 | H63 D Heterozygous (HD) | 65 | 16.8 |
| H63 D Homozygous (DD) | 3 | 0.5 | H63 D Homozygous (DD) | 4 | 1.0 |
| Hardy-Weinberg equilibrium: χ2 = 0.02, p = 0.87 | Hardy-Weinberg equilibrium: χ2 = 0.11, p = 0.74 | ||||
| TF (P570S) | TF (P570S) | ||||
| P570 Wildtype (PP) | 429 | 80.9 | P570 Wildtype (PP) | 319 | 82.0 |
| P570 S Heterozygous (PS) | 100 | 18.9 | P570 S Heterozygous (PS) | 68 | 17.5 |
| P570 S Homozygous (SS) | 1 | 0.2 | P570 S Homozygous (SS) | 2 | 0.5 |
| Hardy-Weinberg equilibrium: χ2 = 3.81, p = 0.05 | Hardy-Weinberg equilibrium: χ2 = 0.65, p = 0.42 | ||||