Table 3.

Predictors of malaria rapid diagnostic test (RDT) specificity (RDT negative, expert microscopy negative) in Blantyre, Malawi, 2009

	Specificity n/N(%)	Unadjusted odds ratio (P value)	Adjusted odd ratio Model 1 (P value)	Adjusted odds ratio Model 2 (P value)
RDT type
Bioline SD	109/283 (39)	0.5 (< 0.001)	0.5 (< 0.001)
First response malaria	128/307 (42)	0.6 (< 0.001)	0.7 (0.01)
Paracheck	530/776 (68)	1.8 (< 0.001)	2.1 (< 0.001)
ICT diagnostics	311/574 (54)	Referent	Referent
Age
5 to ≤ 15 yrs	278/680 (41)	0.4 (< 0.001)	0.4 (< 0.001)	0.4 (< 0.001)
> 15 yrs	778/1211 (64)	Referent	Referent	Referent
Temperature
≥37.5°C	422/790 (53)	0.8 (0.03)	0.8 (0.02)	0.9 (0.20)
< 37.5°C	640/1092 (59)	Referent	Referent	Referent
Self-treated with antimalarial in past 2 weeks
Yes	126/254 (50)	0.7 (0.02)	0.7 (0.05)	0.5 (< 0.001)
No	920/1605 (57)	Referent	Referent	Referent
RDT performed by:
Community health worker	346/810 (43)	0.4 (< 0.001)		0.4 (< 0.001)
Laboratory technician	732/1130 (65)	Referent		Referent

Model 1 assesses RDT type adjusted for patient age, temperature and self-treatment with anti-malarials.

Model 2 assesses RDT test operator (community health worker versus laboratory technician) RDT test operator adjusted for patient age, temperature and self-treatment with anti-malarials.