Table 5.
Survival and p-values with focus on subgroups of GIST regarding Cyclin H expression
| High-Risk | DSS | DFS | ||||
|---|---|---|---|---|---|---|
| Cyclin H |
positive (n = 11) |
negative (n = 28) |
all (n = 39) |
positive (n = 11) |
negative (n = 28) |
all (n = 39) |
| 1-year probability (%) | 75 | 93 | 89 | 51 | 53 | 52 |
| 3-year probability (%) | 50 | 77 | 71 | 26 | 49 | 44 |
| 5-year probability (%) | 33 | 73 | 65 | 26 | 41 | 38 |
| Log-Rank Test (p) | p = 0.038 | p = 0.522 | ||||
| Tumour Recurrence or Metastases | DSS | DFS | ||||
| Cyclin H |
positive (n = 7) |
negative (n = 20) |
all (n = 27) |
positive (n = 7) |
negative (n = 20) |
all (n = 27) |
| 1-year probability (%) | 67 | 90 | 84.9 | 27 | 30 | 30 |
| 3-year probability (%) | 33 | 64 | 57.0 | 0 | 25 | 19 |
| 5-year probability (%) | 0 | 58 | 47.5 | 0 | 10 | 7 |
| Log-Rank Test (p) | p = 0.016 | p = 0.362 | ||||
(results of immunostaining)