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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Comp Biochem Physiol B Biochem Mol Biol. 2010 Apr 22;156(4):298–308. doi: 10.1016/j.cbpb.2010.04.008

Figure 2. Phylogenetic relationship among MDM2 and MDM4 proteins of diverse species indicates that the Mytilus MDM protein may be an ancestral form of vertebrate MDM2 and MDM4.

Figure 2

The un-rooted neighbor-joined consensus tree was based on a pairwise ClustalX alignment, bootstrapped 1000 times. The bottom scale measures genetic distances in substitutions per nucleotide. Records labeled “prd” (predicted) were derived from published genomic sequences without supporting cDNA evidence and annotated using the gene prediction method GNOMON by NCBI. GenBank accession numbers are provided in Table 1.