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. 2010 Aug 5;341:c3967. doi: 10.1136/bmj.c3967

Table 3.

 Crude and adjusted odds ratios of adverse pregnancy outcomes for different interpregnancy intervals

Second pregnancy outcomes Interpregnancy intervals (months)
<6 12-18 18-24 >24
Miscarriage:
 Crude odds ratio (95% CI) 0.77 (0.71 to 0.84)* 0.97 (0.85 to 1.10) 1.01 (0.88 to 1.17) 0.96 (0.86 to 1.06)
 Adjusted† odds ratio (95% CI) 0.66 (0.57 to 0.77)* 0.98 (0.80 to 1.21) 0.99 (0.78 to 1.27) 0.99 (0.84 to 1.18)*
Ectopic pregnancy:
 Crude odds ratio (95% CI) 0.48 (0.34 to 0.69)* 0.99 (0.62 to 1.56) 0.64 (0.34 to 1.21) 1.87 (1.36 to 2.58)*
 Adjusted† odds ratio (95% CI) 0.48 (0.34 to 0.69)* 0.99 (0.63 to 1.57) 0.65 (0.34 to 1.23) 1.97 (1.42 to 2.72)*
Termination:
 Crude odds ratio (95% CI) 0.48 (0.41 to 0.56)* 1.22 (1.01 to 1.47)* 1.54 (1.26 to 1.88)* 2.21 (1.93 to 2.54)*
 Adjusted† odds ratio (95% CI) 0.43 (0.33 to 0.57)* 1.15 (0.83 to 1.59) 1.55 (1.10 to 2.19)* 2.40 (1.91 to 3.01)*
Stillbirth:
 Crude odd ratio (95% CI) 0.72 (0.51 to 1.03) 1.26 (0.79 to 2.02) 0.95 (0.52 to 1.75) 0.98 (0.64 to 1.50)
 Adjusted† odds ratio (95% CI) 0.70 (0.38 to 1.29) 1.20 (0.54 to 2.67) 0.83 (0.28 to 2.44) 1.07 (0.54 to 2.15)

Reference category was interpregnancy interval of 6-12 months. Interaction terms interpregnancy interval × year of admission in five year bands were entered into the model, but only that for miscarriage was statistically significant.

*P<0.05.

†Adjusted for maternal age at first pregnancy, Carstairs social deprivation category, and year of first pregnancy.