Table 1.
Patient and tumor characteristics for the 359 tumors
Number of tumors | 359 |
Number of primary tumors | 346 |
Number of primary BRCA1-mutated tumors | 17 |
Number of primary BRCA2-mutated tumors | 31 |
Number of primary familial non-BRCA1/2 tumors | 126 |
Tumor size | |
≤20 mm | 145 (45%) |
> 20 mm | 175 (55%) |
Mean size mm (SD) | 25.8 (15) |
Histologic grading | |
Grade 1 | 26 (11%) |
Grade 2 | 100 (43%) |
Grade 3 | 106 (46%) |
Estrogen-receptor status | |
Positive | 227 (66%) |
Negative | 119 (34%) |
Progesterone-receptor status | |
Positive | 194 (57%) |
Negative | 149 (43%) |
Lymph-node status | |
Negative | 190 (58%) |
Positive | 137 (42%) |
Age | |
Median age, years (range) | 49 (27-88) |
< 50 years | 182 (51%) |
≥ 50 years | 174 (49%) |
Classification according to Hu et al. [4] | |
Basal-like | 79 (22%) |
Normal-like | 34 (9%) |
HER2-enriched | 34 (9%) |
Luminal A | 95 (26%) |
Luminal B | 70 (19%) |
Unclassified | 47 (13%) |
Overall survival | |
Median overall survival in years (range) | 8.1 (0.24-32) |
Median overall survival in years for patients still alive (range) | 12.8 (1.55-20.2) |
Survival is given for the 346 patients from whom primary tumors were available.