Fig. 4.

Venn diagram of changes in gene expression that are common and unique to ischemic (ICM), idiopathic dilated (DCM) and viral cardiomyopathy (VCM). ANOVA testing was performed on the change in gene expression in DCM, ICM, and VCM hearts, relative to NF hearts, for the ensemble of innate immune genes displayed in Table 2. There were 37, 37, and 27 transcripts, respectively, in DCM, ICM, and VCM hearts. The Venn diagram depicts the number of innate immune genes whose changes in gene expression that are common to all forms of cardiomyopathy (n = 14), those that are common to DCM and ICM (n = 21 [14 + 7]), those that are common to ICM and VCM (n = 22 [14 + 8), those that are common to VCM and ICM (n = 15 [14 + 1]), and those that are unique to DCM alone (n = 8), those that are unique to ICM (n = 15), and those that are unique to VCM (n = 4).