TABLE 3.
Isolation of HTLV-III from patients with AIDS and pre-AIDS
| Patient | Diagnosis | Origin | Virus expression |
|||
|---|---|---|---|---|---|---|
| RT Activity (×104 cpm) | Percent positive cells in immune fluorescence assay |
Electron microscopy | ||||
| Rabbit anti-serum | Serum from E.T. | |||||
| R.F. | AIDS (heterosexual) | Haiti | 0.25 | 80 | 33 | ND |
| S.N. | Hemophiliac (lymphadenopathy) | United States | 6.3 | 10 | ND | + |
| B.K. | AIDS (homosexual) | United States | 0.24 | 44 | 5 | + |
| L.S. | AIDS (homosexual) | United States | 0.13 | 64 | 19 | + |
| W.T. | Hemophiliac (lymphadenopathy) | United States | 3.2 | 69 | ND | ND |
The percentage of T cells positive for viral antigen ranged from 10 to 80 percent, as determined by immune fluorescence assays with serum from patient E.T. and with antiserum from rabbits infected repeatedly with disrupted HTLV-III. (from Popovic, et al. [25] with permission)-S.N. and W.T. were from the UNC Center.