. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Calcif Tissue Int. 2010 May 7;86(6):484–494. doi: 10.1007/s00223-010-9365-0

Table 1.

μCT analysis of th3/+ and th3/th3 mice compared to their controls at age 4 months.

	th3/+	WT	th3/th3	IR	WT
Trabecular bone
BMD (mg/mm³)	792 ± 10	837 ± 18^*	797 ± 25	820 ± 9.5	825 ± 21^*
BV/TV (%)	13.9 ± 2.4	19.7 ± 1.8^*	12.1 ± 2.3	16.4 ± 2.5	18.2 ± 1.6^*
Trabecular Number (N/mm)	4.13 ± 0.6	4.97 ± 0.6^**	3.98 ± 0.1	4.35 ± 0.3	4.90 ± 0.7^**
Trabecular Thickness (μm)	41.6 ± 4	48.7 ± 3^**	40.9 ± 3	48.7 ± 3	49.3 ± 2^*
Trabecular Spacing (μm)	275 ± 38	220 ± 35^†	281 ± 44	248 ± 25	229 ± 27 ^**

Cortical Bone
Cortical thickness (mm)	0.14 ± 0.007	0.18 ± 0.008^**	0.16± 0.01	0.16 ± 0.005	0.19 ± 0.01
Inner Perimeter (mm)	4.2 ± 0.1	3.8 ± 0.2^**	3.9 ± 0.1	3.7 ± 0.15	3.8 ± 0.1
Outer Perimeter (mm)	4.5 ± 0.1	4.8 ± 0.2^†	4.7 ± 0.1	4.8 ± 0.3	4.7 ± 0.3
Cortical Area (mm²)	0.61 ± 0.04	0.75 ± 0.03^**	0.69 ± 0.01	0.70 ± 0.02	0.70 ± 0.03
Marrow Area (mm²)	1.15 ± 0.09	0.9 ± 0.1^**	0.9 ± 0.1	0.95 ± 0.2	0.94 ± 0.2

P<0.01;

^**

p<0.05

^†

p=trend

Values are expressed as mean ± SD

WT: wild type control; IR: irradiated control