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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Mol Microbiol. 2010 Feb 28;76(2):393–408. doi: 10.1111/j.1365-2958.2010.07103.x

Figure 4.

Figure 4

Analysis of the antibody response to B. burgdorferi B31-5A4 wildtype or ospC transgenic strains in mice. ELISAs were conducted using serum harvested from mice 4 weeks after needle inoculation (infecting strain indicated along the X axis). The sera were serially diluted, screened against immobilized whole B. burgdorferi B31-5A4 wild type cells and titers calculated for each mouse at 1/3 ODmax (indicated by triangles). Geometric means are indicated by horizontal lines. In panel B, immunoblots of whole cell lysates of B. burgdorferi B31-5A4 wild type were screened with serum collected 4 weeks after inoculation with wild type or transgenic B. burgdorferi B31strains (as indicated above each lane).