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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Biomaterials. 2010 Jun 26;31(27):7132–7138. doi: 10.1016/j.biomaterials.2010.06.008

Table 1.

In vitro characteristics of PLGA nano/microspheres

Diameter (nm)1, 2 Polydispersity Index
± S.D.		 ζ-potential (mV)
± ζ deviation1 		GdDTPA contents
(nmol/mg NPs) ± S.D.		 5-FU contents
(nmol/mg NPs) ± S.D.
NS-GdDTPA/SPIO/5-FU 194 ± 10 0.095 ± 0.042 −2.2 ± 0.5 12.8 ± 2.7 4.3 ± 0.7
MS-GdDTPA/SPIO/5-FU 2612 ± 1137 0.801 ± 0.273 −7.0 ± 1.6 90.6 ± 18.4 7.0 ± 1.7
1

Nanoparticles were dispersed in PBS (pH 7.4) for the size measurement, and dispersed in 10 mM of NaCl for the ζ-potential measurement.

2

The hydrodynamic diameter of nanoparticles was calculated by the Stokes-Einstein equation.