. Author manuscript; available in PMC: 2010 Aug 6.

Published in final edited form as: Arch Otolaryngol Head Neck Surg. 2007 May;133(5):495–502. doi: 10.1001/archotol.133.5.495

Table 1.

Summary population data. MTEC's transduced with retroviruses containing oncogenes with clonal populations obtained in lines that survived subcloning. E6 and E6/E7 conferred immortality; however, H-Ras was necessary for tumor growth in vivo.

Retrovirus	PD time (days)	Immortal	% clones immortal	AI Growth	Growth in vivo
Retrovirus	PD time (days)	Immortal	% clones immortal	AI Growth	oral	flank
none	54	-	0/10	-	nt	0/6
lxsn	53	-	0/10	-	nt	0/6
ras	52	-	0/10	-	nt	0/6
E6	12	+	10/10	+	nt	0/6
E7	50	-	^*	nt	nt	0/6
E6/E7	12	+	10/10	+	nt	0/6
E6+ras	12	+	nt	+	nt	7/10
E6/E7+ras	12	+	nt	+	10/12	8/10

nt = “not tested.”

= cells did not survive selection.