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. 2010 Aug 6;5(8):e11843. doi: 10.1371/journal.pone.0011843

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Gkirtzou et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Average distance distributions for the Top Scoring candidates provided by MatureBayes (red) and BayesMiRNAfind (blue) on a common human/mouse blind test set. The set consisted of 181 miRNA precursors which were correctly predicted by BayesMiRNAfind to contain a mature miRNA. BayesMiRNAfind correctly identified the functional stem for 104/181, which were used for the respective distance distribution. The distance distribution for MatureBayes was generated using 85/181 precursors for which the correct stem was predicted, using the Top Scorer procedure. The statistical difference between the two distributions was evaluated using the Kolmogorov-Smirnov Test, confirming that the two datasets come from different distributions (p-value).

Inline graphic — Average distance distributions for the Top Scoring candidates provided by MatureBayes (red) and BayesMiRNAfind (blue) on a common human/mouse blind test set. The set consisted of 181 miRNA precursors which were correctly predicted by BayesMiRNAfind to contain a mature miRNA. BayesMiRNAfind correctly identified the functional stem for 104/181, which were used for the respective distance distribution. The distance distribution for MatureBayes was generated using 85/181 precursors for which the correct stem was predicted, using the Top Scorer procedure. The statistical difference between the two distributions was evaluated using the Kolmogorov-Smirnov Test, confirming that the two datasets come from different distributions (p-value).