Table 2. Frequencies of mtDNA sub-haplogroups in AD patients and controls from Italy.

Sub-haplogroupa	AD patients			Controls
	(N = 936)			(N = 776)
	N	%	SEb	N	%	SEb
H*	182	19,4	0,0129	156	20,1	0,0144
H1	115	12,3	0,0107	97	12,5	0,0119
H3	28	3,0	0,0056	18	2,3	0,0054
H5c	39	4,2	0,0065	18	2,3	0,0054
H6	33	3,5	0,0060	21	2,7	0,0058
J1	64	6,8	0,0082	49	6,3	0,0087
J2	14	1,5	0,0040	13	1,7	0,0046
R0	46	4,9	0,0071	46	5,9	0,0085
T1	21	2,2	0,0048	17	2,2	0,0053
T2	84	9,0	0,0093	70	9,0	0,0103
U*	38	4,1	0,0065	32	4,1	0,0071
K	67	7,2	0,0084	68	8,8	0,0102
U4	23	2,5	0,0051	16	2,1	0,0051
U5a	46	4,9	0,0071	38	4,9	0,0077
U5b	18	1,9	0,0045	22	2,8	0,0060
V	31	3,3	0,0058	29	3,7	0,0068
W	20	2,1	0,0047	16	2,1	0,0051
X	26	2,8	0,0054	15	1,9	0,0049
Other	41	4,4	0,0067	35	4,5	0,0074

^aSub-haplogroups with frequencies lower than 1.5% were grouped. Thus R0 includes R0a, R1, HV*, HV0*, HV0a, HV1 and HV2; H* includes all mtDNAs belonging to haplogroup H, except those further classified (H1, H3, H5 and H6); the same rationale has been used for U*; whereas “Other” contains the heterogeneous haplogroups I, L1b, L2a, L2c, L3d, L3e, M, N and N1.

^bStandard Error.

^cOnly for H5 there is a difference between AD patients and controls with a χ² p-value (not adjusted for multiple comparisons) of 0.034.