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. 2010 Aug 6;5(8):e12037. doi: 10.1371/journal.pone.0012037

Table 6. Number of mutations found along the mtDNA molecule regions in AD patients (N = 936) vs controls (N = 776).

mtDNA region N. mutations in AD (N = 534) N. mutations in CNT (N = 261)
D-loop 235 115
ND1 4 2
ND2 44 24
COI 3 3
COII 5 3
ATPase8 1 1
ATPase6 41 24
COIII 1 0
ND3 6 2
ND4L 1 1
ND4 7 6
ND5 16 5
ND6 4 2
CytB 52 25
Total (genes) 185 98
Y 1 0
R 5 5
T 2 0
C 1 0
Q 19 6
K 3 0
F 2 0
S 1 0
S2 0 1
Total (tRNA) 34 12
12S 80 36
Total (rRNA) 80 36