Table 1.
Prevalence of patient and tumor characteristics by age
| Characteristics | Age 0–5 years | Age 6–19 years | p-value |
|---|---|---|---|
| n = 49 | n = 1687 | ||
| Median age (range) | 4 years (0 – 5) | 14 years (6 – 19) | |
| Male | 46.9% (23) | 56.4% (952) | 0.19 |
| Stage | |||
| Metastatic | 12.2% (6) | 17.7% (299) | 0.48 |
| Localized | 77.6% (38) | 75.2% (1268) | |
| Unknown | 10.2% (5) | 7.1% (120) | |
| Histology | |||
| Osteosarcoma, NOS | 79.6% (39) | 78.7% (1327) | 0.098* |
| Chondroblastic | 8.2% (4) | 11.9% (200) | |
| Fibroblastic | 2% (1) | 4.1% (69) | |
| Telangiectatic | 10.2% (5) | 2.9% (50) | |
| Other histologies | 0% | 2.4% (41) | |
| Site | |||
| Upper limb | 24.5% (12) | 11.2% (189) | 0.006 |
| Lower limb | 59.2% (29) | 78% (1315) | |
| Other sites | 16.3% (8) | 10.9 (183) | |
| Race/Ethnicity | |||
| White non-Hispanic | 53.1% (26) | 54.8% (924) | 0.43 |
| Asian non-Hispanic | 4.1% (2) | 9.8% (165) | |
| Black non-Hispanic | 14.3% (7) | 14.2% (240) | |
| White Hispanic | 20.4% (10) | 16.9% (285) | |
| Unknown or Other | 8.2% (4) | 4.3% (73) | |
| Year of diagnosis | |||
| 1973 – 1977 | 6.1% (3) | 7.6% (128) | 0.76 |
| 1978 – 1982 | 12.2% (6) | 9.1% (153) | |
| 1983 – 1987 | 8.2% (4) | 8.7% (147) | |
| 1988 – 1992 | 16.3% (8) | 9.7% (164) | |
| 1993 – 1997 | 12.2% (6) | 14.2% (240) | |
| 1998 – 2002 | 20.4% (10) | 25.6% (431) | |
| 2003 – 2006 | 24.5% (12) | 25.1% (424) | |
*
P-value reflects overall difference in histologic subtypes between age groups. P-value for difference in telangiectatic subtype compared to all other histologies between age groups was 0.017.